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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUX1
All Species:
24.24
Human Site:
S185
Identified Species:
44.44
UniProt:
P39880
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P39880
NP_853530.2
1505
164273
S185
K
L
Q
E
T
Q
M
S
T
T
S
K
L
E
E
Chimpanzee
Pan troglodytes
XP_527845
1515
165612
S196
K
L
Q
E
T
Q
M
S
T
T
S
K
L
E
E
Rhesus Macaque
Macaca mulatta
XP_001114534
1791
194745
S462
K
L
Q
E
T
Q
M
S
T
T
S
K
L
E
E
Dog
Lupus familis
XP_546939
1411
154543
V167
E
L
D
A
T
A
T
V
L
A
N
R
Q
D
E
Cat
Felis silvestris
Mouse
Mus musculus
P53564
1515
165577
S185
K
L
Q
E
T
Q
M
S
T
T
S
K
L
E
E
Rat
Rattus norvegicus
P53565
862
92341
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506212
1543
168501
T231
G
V
Q
E
T
Q
I
T
L
A
A
R
L
G
E
Chicken
Gallus gallus
XP_425393
1673
183755
S330
K
L
Q
E
T
Q
M
S
T
A
S
K
L
E
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693902
1398
154481
L153
V
R
L
D
Q
A
E
L
R
I
K
A
L
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P10180
2175
233610
R451
A
L
L
D
E
L
Q
R
L
R
A
Q
E
Q
T
Honey Bee
Apis mellifera
XP_623857
1936
209316
E233
R
T
P
N
T
N
L
E
Q
E
L
Q
A
K
D
Nematode Worm
Caenorhab. elegans
Q9BL02
1273
143507
I88
A
E
N
A
L
I
D
I
C
K
S
I
V
S
L
Sea Urchin
Strong. purpuratus
XP_780858
1460
163719
S197
Q
L
Q
E
K
Q
M
S
V
A
K
K
L
G
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
83.1
56.2
N.A.
88.8
47.1
N.A.
44.3
77.4
N.A.
40.9
N.A.
23.3
23.7
22.3
29.1
Protein Similarity:
100
98.6
83.4
64.5
N.A.
91.8
50
N.A.
60
81.7
N.A.
55.4
N.A.
37.4
41
41
46.6
P-Site Identity:
100
100
100
20
N.A.
100
0
N.A.
40
93.3
N.A.
6.6
N.A.
6.6
6.6
6.6
60
P-Site Similarity:
100
100
100
46.6
N.A.
100
0
N.A.
73.3
93.3
N.A.
20
N.A.
33.3
40
13.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
16
0
16
0
0
0
31
16
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
8
16
0
0
8
0
0
0
0
0
0
8
8
% D
% Glu:
8
8
0
54
8
0
8
8
0
8
0
0
8
39
62
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
0
0
16
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
8
8
0
8
0
8
0
0
0
% I
% Lys:
39
0
0
0
8
0
0
0
0
8
16
47
0
8
0
% K
% Leu:
0
62
16
0
8
8
8
8
24
0
8
0
62
0
8
% L
% Met:
0
0
0
0
0
0
47
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
8
0
8
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
54
0
8
54
8
0
8
0
0
16
8
16
0
% Q
% Arg:
8
8
0
0
0
0
0
8
8
8
0
16
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
47
0
0
47
0
0
8
8
% S
% Thr:
0
8
0
0
62
0
8
8
39
31
0
0
0
0
8
% T
% Val:
8
8
0
0
0
0
0
8
8
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _